Astrocyte-specific inhibition of primary cilium functions improves cognitive impairment during neuroinflammation by suppressing A1 astrocyte differentiation.
Nor Atiqah Muhamad, Shota Furukawa, Shunsuke Yuri, Michinori Toriyama, Kohei Masutani, Chuya Matsumoto, Seiya Itoh, Yuichiro Shinagawa, Ayako Isotani, Manami Toriyama, Hiroshi Itoh
The paper shows that inhibiting astrocyte primary cilia reduces A1 astrocyte differentiation and improves cognitive impairment in neuroinflammation.
bioRxiv · Oct 1, 2023 · PreprintNeuroscience