Author

Manfei Bella Xie

Vanderbilt University

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Biology Disciplines

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Bioinformatics· 1

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Derek M Young· 1 shared Haoran QiniD· 1 shared Qimeng WangiD· 1 shared Shan MeltzeriD· 1 shared Weiman Yuan· 1 shared Wenjun SheniD· 1 shared Xin ZhouiD· 1 shared Yichen Henry LiuiD· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Derek M Young

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintJun 22, 2026

Benchmarking cell type annotation in spatial transcriptomics: resolving cellular hierarchies, biological fidelity, and dynamic cell states

Yuling Zhu, Yunfei Hu, Manfei Bella Xie…·Xin Zhou

This study benchmarks 20 cell type annotation methods on spatial transcriptomics data to evaluate their performance in resolving cell types, subtypes, and biological organization across diverse datasets.

DOI 10.64898/2026.06.16.732716

spatial transcriptomicsbenchmark study