Functional Genomics Screen with Pooled shRNA Library and Gene Expression Profiling with Extracts of Azadirachta indica Identify Potential Pathways for Therapeutic Targets in Head and Neck Squamous Cell Carcinoma
Neeraja M. Krishnan, Hiroto Katoh, Vinayak C. Palve, Manisha Pareek, Reiko Sato, Shumpei Ishikawa, Binay Panda
The paper identifies 225 genes and pathways, including TGF-β and HSF-1, affected by neem extract in head and neck squamous cell carcinoma using shRNA screening and gene expression analysis.
PeerJ · Mar 1, 2019Peer-reviewedGenomics