Leveraging the genetics of human face shape boosts the discovery of orofacial cleft risk loci
Noah Herrick, Seppe Goovaerts, Alexandra Manchel, Myoung Keun Lee, Xiangyu Zhang, Amy Davies, Jenna C. Carlson, Elizabeth J. Leslie, Sarah Jane Lewis, Marazita Ml, Cotney Justin, Peter D. Claes, John R. Shaffer, Seth M. Weinberg
This study uses a pleiotropy-informed GWAS method to identify new orofacial cleft risk loci by leveraging genetic associations with facial shape.
Human Genetics and Genomics Advances · Jul 22, 2026Peer-reviewedGenetic & Genomic Medicine