Author

Xiangyu Zhang

University of PittsburghORCID 0000-0002-1932-1598Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiangyu Zhang2 papers · Peking University People's Hospital

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

Alejandro PizzoniiD· 1 shared Alexandra MancheliD· 1 shared Alípio PintoiD· 1 shared Àmarjit Singh· 1 shared Amy DaviesiD· 1 shared Cotney JustiniD· 1 shared Daniel L. AltschuleriD· 1 shared Elizabeth J. LeslieiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

Alejandro PizzoniORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 9, 2026

Photobiocatalytic Diastereo- and Enantioselective Synthesis of Non-Canonical Amino Acids Bearing Challenging Stereochemical Dyads and Triads

Zhiyu Bo, Lei Cheng, Xiangyu Zhang…·Yang Yang

This paper develops engineered PLP-dependent biocatalysts for stereodivergent synthesis of non-canonical amino acids with complex stereochemical arrays, achieving high stereoselectivity and yield.

DOI 10.64898/2026.10.07.757362

proteomicsexperimental assay

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Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedJul 22, 2026

Leveraging the genetics of human face shape boosts the discovery of orofacial cleft risk loci

Noah Herrick, Seppe Goovaerts, Alexandra Manchel…·Seth M. Weinberg

This study uses a pleiotropy-informed GWAS method to identify new orofacial cleft risk loci by leveraging genetic associations with facial shape.

DOI 10.1016/j.xhgg.2026.100655

humanGWAS summary statistics

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Cell BiologybioRxivPreprintMay 11, 2026

Rap1 Activates Endosomal AC9 to Drive the Second cAMP Wave

Xiangyu Zhang, Alejandro Pizzoni, Alípio Pinto, Daniel L. Altschuler

The paper identifies Rap1b as a direct activator of endosomal AC9, revealing a new mechanism for the endosomal cAMP wave in GsPCR signaling.

1 citation

experimental assaycell signaling & trafficking

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