A computational model elucidates the effect of oncogene induced expression alterations on the energy metabolism of neuroblastoma
Mareike Simon, Uwe Benary, Katharina Baum, Alexander R. Schramm, Jana Wolf
The paper develops a computational model to analyze how MYCN-induced expression changes affect energy metabolism in neuroblastoma, revealing Warburg-like flux alterations and potential metabolic bistability.
Scientific Reports · Sep 24, 2025Peer-reviewedSystems Biology