Author

Marguerite Clarke

Institute of Genetics and Cancer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Atul KumariD· 1 shared Christine J. RodgeriD· 1 shared Christine KleiniD· 1 shared Dario R. AlessiiD· 1 shared Dipti Ranjan LenkaiD· 1 shared Duncan SprouliD· 1 shared Esther M. SammleriD· 1 shared Grzegorz R. KudlaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Atul KumarORCID

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1 paper

Recent·Most cited

A Functional Genetic Atlas of Parkin Resolves Variants of Uncertain Significance and Predicts Parkinson's Disease Age at Onset

Vahid Aslanzadeh, Sophie Glendinning, Yustika Sari, Marguerite Clarke, Christine J. Rodger, Xiaoyi Lin, Dipti Ranjan Lenka, Lucy Richardson, Jin Rui Liang, Teresa Kleinz, Duncan Sproul, Katja Lohmann, Christine Klein, Esther M. Sammler, Dario R. Alessi, , Grzegorz R. Kudla

The paper functionally characterizes PRKN variants using a pooled assay, reclassifies variants of uncertain significance, and predicts Parkinson's disease age at onset.

bioRxiv · Feb 9, 2026 · PreprintGenetics