ZZZ3 protects human embryonic stem cells from nucleolar stress by boosting mTOR/ribosome pathway.
Michela Lo Conte, Valeria Lucchino, Stefania Scalise, Clara Zannino, Maria Stella Murfuni, Chiara Cicconetti, Luana Scaramuzzino, Danilo Swann Matassa, Anna Procopio, Giovanni Cuda, Elvira Immacolata Parrotta
This study shows that ZZZ3 supports human ESC proliferation by enhancing mTOR/ribosome pathway activity and preventing nucleolar stress.
bioRxiv · Sep 8, 2023 · PreprintMolecular Biology