Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR
Michael Scherer, Gilles Gasparoni, Souad Rahmouni, Tatiana Shashkova, Marion Arnoux, Edouard J. Louis, Arina V. Nostaeva, Diana Avalos, Emmanouil T. Dermitzakis, Yurii S. Aulchenko, Thomas Lengauer, Paul Lyons, Michel Georges, Jörn Walter
The paper introduces MAGAR, a framework to identify methylation quantitative trait loci (methQTLs) and distinguish common from cell-type-specific effects using DNA methylation and genotyping data.
Epigenetics & Chromatin · Sep 16, 2021Peer-reviewedGenetics