Author

Masataka Akagawa

Chiba University

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Biochemistry· 1

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Approach:statistical model· 1

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Akira SassaiD· 1 shared Kaoru SugasawaiD· 1 shared Kiyoe UraiD· 1 shared

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2025-2025 · peak 1/yr

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Akira SassaORCID

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1 paper

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedApr 16, 2025

Impact of an Oxidative RNA Lesion on in vitro Replication Catalyzed by SARS-CoV-2 RNA-dependent RNA Polymerase

Masataka Akagawa, Kaoru Sugasawa, Kiyoe Ura, Akira Sassa

This study examines how SARS-CoV-2 RNA-dependent RNA polymerase replicates past an oxidative RNA lesion, finding that it preferentially incorporates rCMP and has higher bypass efficiency for rA:8-oxo-rG than rC:8-oxo-rG.

7 citations

statistical model

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