Dissecting signalling hierarchies in the patterning of the mouse primitive streak using micro-patterned EpiLC colonies.
Jean-Louis Plouhinec, Mathieu Vieira, Gaël Simon, Jérôme Collignon, Benoît Sorre
The paper investigates the roles of WNT, BMP, and NODAL signalling pathways in mouse primitive streak patterning using micro-patterned EpiLC colonies, showing BMP dominance and NODAL's role in mesendoderm establishment.
bioRxiv · Nov 30, 2020 · PreprintDevelopmental Biology