A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluation
Robert Yang, Jie Quan, Reza Sodaei, François Aguet, Ayellet V. Segrè, John Allen, Thomas A. Lanz, Veronica Reinhart, Matthew E. Crawford, Samuel A. Hasson, Kristin Ardlie, Roderic Guigó, Hualin Simon Xi
The paper analyzes tissue-specific gene expression and splicing across 8527 RNA-seq samples to identify therapeutic targets and prioritize disease-associated genes.
bioRxiv · Apr 30, 2018 · PreprintGenomics