MEIOC prevents continued mitotic cycling and promotes meiotic entry during mouse oogenesis
Esther G. Ushuhuda, Jenniluyn T. Nguyen, Natalie G. Pfaltzgraff, Shelbie M. Wenner, Matthew Kofron, Maria M. Mikedis
This study shows MEIOC halts mitotic cycling and promotes meiotic entry in mouse oocytes by repressing CCNA2 and upregulating Meiosin through a positive feedback loop with STRA8-MEIOSIN.
Development · Nov 25, 2025Peer-reviewedDevelopmental Biology