Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging
Mohamad M. Kronfol, Sara Abudahab, Mikhail G. Dozmorov, Fay M. Jahr, Matthew S. Halquist, MaryPeace McRae, Dayanjan S. Wijesinghe, Elvin T. Price, Patricia W. Slattum, Joseph L. McClay
The paper examines age-related epigenetic changes in Sult1a1 and Ugt1a6 genes in mice, finding significant loss of DNA methylation and increased H3K9ac at Sult1a1, with H3K9ac positively correlating with gene expression.
Pharmacogenetics and Genomics · Jul 26, 2021Peer-reviewedGenetics