Pharmacology & ToxicologybioRxivPreprint
Assessment of pharmacokinetics, safety, and neuroprotective efficacy of an adjunct intramuscular verapamil therapy in a rat model of organophosphate DFP-induced status epilepticus
Yam Nath Paudel, Robert E. Blair, Elisa Hawkins…·Laxmikant S. Deshpande
This study evaluates the safety, pharmacokinetics, and neuroprotective effects of intramuscular verapamil in a rat model of organophosphate-induced status epilepticus, showing improved brain levels and neuroprotection compared to oral administration.
DOI 10.1101/2025.06.25.661332