Glycosylation Flux Analysis Reveals Dynamic Changes Of Intracellular Glycosylation Flux Distribution In Chinese Hamster Ovary Fed-Batch Cultures
Sandro Hutter, Thomas K. Villiger, David Brühlmann, Matthieu Stettler, Hervé Broly, Miroslav Šoóš, Rudiyanto Gunawan
This study introduces glycosylation flux analysis to predict intracellular glycosylation fluxes in CHO cells, showing that galactosylation fluxes decrease over time and Mn addition increases them initially.
Metabolic Engineering · Jul 25, 2017Peer-reviewedSystems Biology