Cerebellar white matter development is regulated by fractalkine-dependent microglia phagocytosis of oligodendrocyte progenitor cells
McKenzie K. Chappell, John Shelestak, Muhammad Irfan, Eric Shelestak, Ashley D. Nemes, Gabrielle M. Mey, Lakshmi Venkat, Amulya Surabhi, Tara M. DeSilva
The paper shows that amoeboid microglia engulf oligodendrocyte progenitor cells in the developing cerebellum, with implications for neurodevelopmental disorders.
iScience · Sep 1, 2025Peer-reviewedNeuroscience