Computational investigation unveils pathogenic LIG3 non-synonymous mutations and therapeutic targets in acute myeloid leukemia
Md. Arif Hossen, Umme Mim Sad Jahan, Md. Arju Hossain, Khalid Hossain Asif, Ahona Rahman, Sabbir Ahmed, Md. Moin Uddin, Md Faisal Amin, Muhammad Abdul Bari, Mohammod Johirul Islam, Mohammad Kamruzzaman, Soharth Hasnat, Mohammad Nasir Uddin, Tofazzal Islam, M. Nazmul Hoque
This study identifies deleterious LIG3 nsSNPs and potential therapeutic targets for AML using computational methods and molecular simulations.
PLoS ONE · Jun 10, 2025Peer-reviewedCancer Biology