Characterizing a hallmark of glymphatic insufficiency: Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index and perivascular space
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn D. Roseborough, Meaghan Frank, Qi Zhang, Stephen Pasternak, Robert R Hammond, Shawn Narain Whitehead
The paper examines wasteosome accumulation in periventricular white matter hyperintensities and links it to vascular and pathological features in a mixed diagnostic cohort.
bioRxiv · Jul 25, 2025 · PreprintNeuroscience