A Structural Antibody Benchmark of AlphaFold3 reveals Hallucinated Epitopes and a Bias for Orderness
Arnav Solanki, Neha Shree Maurya, Meaghan Ramlakhan, Rongbin Li, Wenbo Chen, Zhuhao Wu, Wenjin Jim Zheng
This study benchmarks AlphaFold3's antibody-antigen binding predictions using experimental data and identifies biases and false positives in its performance.
bioRxiv · Jul 31, 2026 · PreprintBioinformatics