Phospholipase D1 and Phosphatidic Acid are required for MVE Fusion and Exosome Secretion
Melodie T. Nguyen, Broderick L. Bills, André Allen, Megan L. Hulser, Sisiyan Jiang, Michelle K. Knowles
This study shows that phospholipase D1 (PLD1) and phosphatidic acid (PA) regulate MVE fusion and exosome release by promoting docking-to-fusion transition and correlating with exosome release rate.
Biophysical Journal · Apr 6, 2026Peer-reviewedBiophysics