Impact of inhibitors of histone post-translational modifications on lifespan, reproduction, and stress response in the rotifer Brachionus manjavacas
Nelia Luviano, Meghan Dryburgh, Colleen M. McMaken, Alyssa Liguori, Kristin Elizabeth Gribble
This study investigates the effects of HDAC and SETDB1 inhibitors on lifespan, reproduction, and stress response in rotifers, finding that some treatments extend lifespan and enhance stress tolerance without affecting reproduction.
bioRxiv · May 3, 2025 · PreprintPhysiology