Protein language models enable prediction of polyreactivity of monospecific, bispecific, and heavy-chain-only antibodies
Xin Yu, Kostika Vangjeli, Anusha Prakash, Meha Chhaya, Samantha J Stanley, Noah D. Cohen, Lili Huang
The paper develops deep learning models using protein language models to predict polyreactivity of antibodies, outperforming structure-based models.
Antibody Therapeutics · May 29, 2024Peer-reviewedBioinformatics