Placental malaria is associated with a TLR-Endothelin-3-oxidative damage response in human placenta tissues
Samuel Chenge, Melvin Mbalitsi, Harrison Ngure, Moses Obimbo, Mercy Singoei, Mourine Kangogo, Bernard N. Kanoi, Jesse Gitaka, Francis M. Kobia
This study identifies a TLR-Endothelin-3-oxidative damage response in placental malaria, linking it to adverse pregnancy outcomes through upregulated TLRs, Endothelin-3, and oxidative DNA damage markers.
bioRxiv · Apr 17, 2024 · PreprintCell Biology