The neurodevelopmental transcriptome of the Drosophila melanogaster microcephaly gene abnormal spindle reveals a role for temporal transcription factors and the immune system in regulating brain size
M. Constanza Mannino, Mercedes Bartels Cassidy, Steven Florez, Zeid M. Rusan, Shalini Chakraborty, Todd Andrew Schoborg
This paper identifies transcriptomic signatures and functional pathways disrupted in Drosophila asp mutants, revealing roles for temporal transcription factors and inflammation in microcephaly.
bioRxiv · Jan 9, 2023 · PreprintDevelopmental Biology