Exploring "dark matter" protein folds using deep learning
Zander Harteveld, Alexandra Van Hall‐Beauvais, Ирина Морозова, Joshua Southern, Casper A. Goverde, Sandrine Georgeon, Stéphane Rosset, Michëal Defferrard, Andreas Loukas, Pierre Vandergheynst, Michael M. Bronstein, Bruno E. Correia
This paper introduces a deep learning framework called Genesis to learn protein structural patterns and demonstrates its ability to design novel protein folds with high protease resistance.
Cell Systems · Oct 1, 2024Peer-reviewedBioinformatics