Colocalization of GWAS and eQTL Signals Detects Target Genes
Farhad Hormozdiari, Martijn van de Bunt, Ayellet V. Segre, Xiao Li, Jong Wha J Joo, Michael Bilow, Jae Hoon Sul, Sriram Sankararaman, Bogdan Pasaniuc, Eleazar Eskin
This paper introduces eCAVIAR, a method to compute colocalization posterior probability between GWAS and eQTL signals to identify target genes and tissues for complex traits.
The American Journal of Human Genetics · Dec 1, 2016Peer-reviewedGenetics