Patient-specific detection of cancer genes reveals recurrently perturbed processes in esophageal adenocarcinoma
Thanos P. Mourikis, Lorena Benedetti, Elizabeth Foxall, Damjan Temelkovski, Joel Nulsen, Juliane Perner, Matteo Cereda, Jesper Lagergren, Michael Howell, Christopher Yau, Rebecca C. Fitzgerald, Paola Scaffidi, Francesca D. Ciccarelli, on behalf of the Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium
This study identifies patient-specific cancer genes in esophageal adenocarcinoma using machine learning, revealing recurrent process perturbations that suggest therapeutic targets.
bioRxiv · Oct 17, 2018 · PreprintCancer Biology