Comparison of Different Approaches to Single Cell RNA Sequencing of Cancer Associated Fibroblasts
Heng‐Chung Kung, Michael Loycano, Lei Zheng, Sophia Y. Chen, Jacquelyn W. Zimmerman
This study compares scRNA-seq of unenriched and CAF-enriched samples from PDAC tumors, finding that CAF enrichment better captures heterogeneity but loses other TME cells.
bioRxiv · Apr 29, 2024 · PreprintCancer Biology