mBER: Controllable de novo antibody design with million-scale experimental screening
Erik Swanson, Michael Nichols, Supriya Ravichandran, Pierce Ogden
The paper introduces mBER, a system for designing antibody-format binders with high experimental success rates, achieving 45% success across 145 targets and 38% binding rates to specific epitopes.
bioRxiv · Sep 26, 2025 · PreprintSynthetic Biology