The shrinking human protein coding complement: are there fewer than 20,000 genes?
Iakes Ezkurdia, David Juan, Jose Manuel Rodriguez, Adam Frankish, Mark Deikhans, Jennifer L Harrow, Jesus Vazquez, Alfonso Valencia, Michael Tress
The paper maps peptides from proteomics studies to human genes, finding that only 3% of 2,001 genes with non-protein-like features show peptide detection, suggesting many may not code for proteins.
bioRxiv · Jan 17, 2014Genomics