Author

Michaela Helmel

Boston Children's Hospital

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert T. YoungiD· 1 shared Hanno SteeniD· 1 shared John F QuackenbushiD· 1 shared John PlatigiD· 1 shared Robert N. HussoniD· 1 shared Xavier CaretteiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperSystems Biology

Albert T. YoungORCID

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1 paper

Recent·Most cited

Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis

Albert T. Young, Xavier Carette, Michaela Helmel, Hanno Steen, Robert N. Husson, John F Quackenbush, John Platig

The paper shows that kinase inhibition in Mtb affects regulatory networks, altering cell wall integrity, stress response, and energy production through transcription factor activity changes.

npj Systems Biology and Applications · Jan 29, 2021Peer-reviewedSystems Biology