Author

Robert N. Husson

Boston Children's HospitalORCID 0000-0001-8994-7046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert T. YoungiD· 1 shared Basanti MalakariD· 1 shared Hanno SteeniD· 1 shared John F QuackenbushiD· 1 shared John PlatigiD· 1 shared Júlia PuffaliD· 1 shared Michaela Helmel· 1 shared Nancy A. WoychikiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Albert T. YoungORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of BacteriologyPeer-reviewedSep 24, 2024

Phosphorylation of VapB antitoxins affects intermolecular interactions to regulate VapC toxin activity in Mycobacterium tuberculosis

Basanti Malakar, Valdir C. Barth, Júlia Puffal…·Robert N. Husson

This study shows that phosphorylation of VapB antitoxins in M. tuberculosis alters their interactions with VapC toxins and promoter DNA, thereby regulating toxin activity and bacterial survival.

6 citations

mouseexperimental assay

𝕏 PostBluesky

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedJan 29, 2021

Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis

Albert T. Young, Xavier Carette, Michaela Helmel…·John Platig

The paper shows that kinase inhibition in Mtb affects regulatory networks, altering cell wall integrity, stress response, and energy production through transcription factor activity changes.

7 citations

bulk RNA-seqChIP-seq

𝕏 PostBluesky