Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the outcome of Homologous Recombination.
Fabiola García Fernández, Etienne Almayrac, Ànnia Carré Simon, Renaud Batrin, Yasmine Khalil, Michel Boissac, Emmanuelle Fabre
The paper shows that global chromatin mobility during homologous recombination depends on chromosomal conformation and is essential for repair when the DSB is away from the centromere.
eLife · Sep 9, 2022Peer-reviewedMolecular Biology