Rare predicted loss-of-function variants of type I IFN immunity genes are associated with critical COVID-19
Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jérémy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, , Michel Vidaud
The paper identifies rare loss-of-function variants in type I IFN immunity genes associated with severe COVID-19, particularly in younger patients with recessive inheritance.
Genome Medicine · Apr 5, 2023Peer-reviewedGenetic & Genomic Medicine