Author

Matthieu Chaldebas

InsermORCID 0000-0002-4920-3947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Peng ZhangiD· 2 shared Yoann SeeleuthneriD· 2 shared Adem KarbuziD· 1 shared Adrian GervaisiD· 1 shared Agatha SchlüteriD· 1 shared Ahmad N. Abou TayouniD· 1 shared Alban Lermine· 1 shared Alessandro AiutiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Peng ZhangORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintSep 11, 2026

Mechanistic 5'UTR Variant Scoring Expands Rare Variant Discovery in the UK Biobank

Matthieu Chaldebas, Khoren Ponsin, Haralambos A. Mourelatos…·Aurélie Cobat

The paper introduces 5ULTRA, a machine-learning tool for annotating 5'UTR variants, identifying new gene-phenotype associations in the UK Biobank that are missed by existing methods.

DOI 10.64898/2026.09.09.26362607

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicineGenome MedicinePeer-reviewedApr 5, 2023

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with critical COVID-19

Daniela Matuozzo, Estelle Talouarn, Astrid Marchal…·Michel Vidaud

The paper identifies rare loss-of-function variants in type I IFN immunity genes associated with severe COVID-19, particularly in younger patients with recessive inheritance.

80 citationstop 1%

humanwhole-genome sequencing

𝕏 PostBluesky