Temporal Dynamics of Parvalbumin Interneurons and Perineuronal Nets During Learned Helplessness
Labiba Aziz, Suli Wang, Michele Assef, Dani Dumitriu, Alessia Manganaro
This study examines the temporal dynamics of parvalbumin interneurons and perineuronal nets in the medial prefrontal cortex during learned helplessness, showing predictive recruitment, dynamic PV expression, and stress-induced coupling between PV and PNN in the infralimbic subregion.
bioRxiv · Sep 18, 2026 · PreprintNeuroscience