Dani Dumitriu

Sex-Specific Stress Outcomes Following Acute and Chronic Social Defeat Stress

This study investigates sex-specific stress responses to acute and chronic social defeat stress, finding differences in behavioral outcomes between males and females.

Temporal Dynamics of Parvalbumin Interneurons and Perineuronal Nets During Learned Helplessness

This study examines the temporal dynamics of parvalbumin interneurons and perineuronal nets in the medial prefrontal cortex during learned helplessness, showing predictive recruitment, dynamic PV expression, and stress-induced coupling between PV and PNN in the infralimbic subregion.

A Novel Localized Tracing Technique to Explore Intra-Amygdala Functional and Structural Connectivity Patterns as Mediators of Individual Variability in Stress Response

The paper develops a novel tracing technique to investigate intra-amygdala connectivity patterns as predictors of individual variability in stress responses, identifying potential biological markers for trait vulnerability.

A severe form of maternal separation in rat consisting of nineteen-day 6-hour daily separation at unpredictable times minimally affects behavior across the lifespan

This study examines the long-term behavioral effects of a severe maternal separation paradigm in rats, finding minimal adverse outcomes across the lifespan.

Brain mitochondrial diversity and network organization predict anxiety-like behavior in mice

The paper examines mitochondrial respiratory chain capacity and its association with stress-related behaviors in mice, identifying brain networks linked to anxiety-like behavior.

Maternal separation affects fronto-cortical activity in rat pups during dam-pup interactions and behavioral transitions

This study shows that maternal separation in rat pups reduces frontal cortex EEG power during dam-pup interactions, suggesting a link between early-life stress and neurodevelopmental impacts.

Prelimbic-amygdala overexcitability mediates trait vulnerability in a novel mouse model of acute social defeat stress

This study identifies preexisting structural and functional differences in the prelimbic-amygdala circuit that mediate vulnerability to acute social defeat stress in male mice.

MouseCircuits.org: An online repository to guide the circuit era of disordered affect

The paper compiles and analyzes circuit data from rodent studies on affective disorders to identify common pathways and highlight the need for integrated approaches.