Persistent circulating autoreactive PD1⁺TIGIT⁺ peripheral helper T cells reflect synovial lymphoid activity and poor response to conventional disease-modifying anti-rheumatic drugs in early rheumatoid arthritis
Jia Yi Hee, Hendrik J. Nel, Oxana Radetskaya, Gabrielle Antonio-Carreon, Carl Coyle, Wittaya Suwakulsiri, Megan S. F. Soon, Pascale Wehr, Mai T. Tran, Garrett S. Dunlap, Deepak A. Rao, Annabelle Small, Soon Wei Wong, Katrina Chakradeo, Michelle Roch, , Ranjeny Thomas
bioRxiv · Jul 30, 2026 · PreprintImmunology