LOSS OF CLDN5 -AND INCREASE IN IRF7- IN THE HIPPOCAMPUS AND CEREBRAL CORTEX OF DIABETIC MICE AT THE EARLY SYMPTOMATIC STAGE.
Marta Carús-Cadavieco, Sandra González de la Fuente, Inés Berenguer, Miguel A. Serrano-Lope, Begoña Aguado, Francesc Xavier Guix, Ernest Palomer, Carlos G. Dotti
The paper identifies gene expression changes in the hippocampus and cerebral cortex of diabetic mice with minor cognitive deficits, highlighting CLDN5 downregulation and IRF7 upregulation as potential contributors to early cognitive decline.
Nutrition and Diabetes · Aug 15, 2024Peer-reviewedNeuroscience