Francesc Xavier Guix

This study shows that BDNF in extracellular vesicles from embryonic and young cortex maintains neuroprotective signaling, while aged vesicles lack BDNF and fail to trigger protection.

This study shows that embryonic cortical extracellular vesicles provide neuroprotection in vitro and in vivo through CaMKIIα-mediated signaling pathways.

The paper identifies gene expression changes in the hippocampus and cerebral cortex of diabetic mice with minor cognitive deficits, highlighting CLDN5 downregulation and IRF7 upregulation as potential contributors to early cognitive decline.