A Simulation of Semi-Infectious Particles and Genome Complementation Reproduces Interferon Response by Respiratory Epithelial Cells in vitro during Influenza A Virus Infection
Pedro C. Dal-Castel, Jessica D. Resnick, James Patrick Sluka, Molly Gallagher, Mika Helfers, I. Bird, Jeremy D. Ratcliff, Sarah L. Grady, James A. Glazier
The paper develops a computational model of influenza A virus infection that simulates semi-infectious particles and genome complementation, showing how these factors influence IFN response and viral load in respiratory epithelial cells.
bioRxiv · May 22, 2026 · PreprintSystems Biology