James A. Glazier

The paper develops a computational model of influenza A virus infection that simulates semi-infectious particles and genome complementation, showing how these factors influence IFN response and viral load in respiratory epithelial cells.

The paper develops an agent-based model of zebrafish epiboly to study force generation and tissue deformation during early development.

V-Cornea models corneal epithelium homeostasis, injury, and recovery, accurately predicting healing times and structural changes following trauma or chemical exposure.

The paper develops a Cellular-Potts model to study how cohesotaxis, tissue geometry, and cell intercalation influence collective migration velocity in Xenopus mesendoderm.

PhenoCellPy provides a Python package to model cell behaviors and states, enabling integration with other modeling frameworks.

The paper uses transcriptogram analysis on SARS-CoV-1 microarray data to identify gene sets and their temporal relationship with viral titer during infection.

This paper uses a Cellular Potts Model to simulate cell movement and aggregation during kidney development, showing that chemoattractant secretion and cell adhesion differences drive NP cell patterning.

The paper develops a spatial multicellular model of RNA virus replication and interferon responses, showing how interferon concentrations and diffusion rates affect plaque growth dynamics.

This paper develops a multiscale spatiotemporal model of influenza infection and immune response, showing that localized viral exposure significantly impacts infection severity.

The paper proposes a mechanical model for early somite segmentation based on apical constriction waves and adhesion failure in chicken embryos.

This study identifies cell intercalation as the primary driver of chick limb bud morphogenesis, using in vivo imaging and computational modeling to reveal the role of molecular gradients and tissue fluidity.

Open-source agent-based PhysiCell model of SARS-CoV-2 infection in lung epithelium; version 5 clears virus in about 6 days in simulation, and delayed T cell arrival increases epithelial loss.