Human genetic evidence supports MAP3K15 inhibition as a therapeutic strategy for diabetes
Abhishek Nag, Ryan S. Dhindsa, Andrew Robert Harper, Dimitrios Vitsios, Andrea Ahnmark, Bilada Bilican, Katja Madeyski-Bengtson, Bader Zarrouki, Quanli Wang, Katherine R. Smith, David M. Smith, Benjamin Challis, Dirk S. Paul, Mohammad Bohlooly‐Y, Mike Snowden, , Slavé Petrovski
The paper identifies MAP3K15 as a protective gene for diabetes through genetic analysis and shows its inhibition could be a therapeutic strategy.
medRxiv · Nov 14, 2021 · PreprintGenetic & Genomic Medicine