Author

Katja Madeyski-Bengtson

AstraZeneca (Sweden)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:GWAS / association mapping· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Anna-Lena Loyd· 2 shared Marcello MarescaiD· 2 shared Niklas SelfjordiD· 2 shared Panagiotis AntoniouiD· 2 shared Abhishek NagiD· 1 shared Aikaterini EmmanouilidiiD· 1 shared Alexandra MadseniD· 1 shared Andrea AhnmarkiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Anna-Lena Loyd

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-Cell and Tissue-Specific CRISPR Editing Analyses Unveil New Insights to Off-Targets and Translocations

Alexandra Madsen, Niklas Selfjord, Marta Martínez-Lage, Anna-Lena Loyd, Gavin Kurgan, Mikaela Stahlberg, Julia Lindgren, Julia Liz Touza, Leif Wigge, Mike A. Firth, Karl J. V. Nordström, Joseph Collin, Daniel Jachimowicz, Bastian Schiffthaler, Inken Dillmann, , Pınar Akçakaya

The paper analyzes CRISPR-Cas9 off-target mutations and translocations at single-cell and tissue-specific levels in mice, revealing context-dependent variability in editing outcomes.

bioRxiv · Jun 10, 2026 · PreprintGenomics

Improved nuclease-based prime editing by DNA repair modulation and pegRNA engineering

Panagiotis Antoniou, Louis Dacquay, Niklas Selfjord, Katja Madeyski-Bengtson, Anna-Lena Loyd, Euan Gordon, George Thom, Pei-Pei Hsieh, Sandra Wimberger, Saša Šviković, Mike Firth, Nina Akrap, Marcello Maresca, Martin Peterka

This paper improves prime editing by modulating DNA repair pathways and engineering pegRNA, achieving higher precision and efficiency in human and mouse cells.

bioRxiv · Feb 1, 2024 · PreprintBioengineering

Human genetic evidence supports MAP3K15 inhibition as a therapeutic strategy for diabetes

Abhishek Nag, Ryan S. Dhindsa, Andrew Robert Harper, Dimitrios Vitsios, Andrea Ahnmark, Bilada Bilican, Katja Madeyski-Bengtson, Bader Zarrouki, Quanli Wang, Katherine R. Smith, David M. Smith, Benjamin Challis, Dirk S. Paul, Mohammad Bohlooly‐Y, Mike Snowden, , Slavé Petrovski

The paper identifies MAP3K15 as a protective gene for diabetes through genetic analysis and shows its inhibition could be a therapeutic strategy.

medRxiv · Nov 14, 2021 · PreprintGenetic & Genomic Medicine