A Recql5 mutant enables complex chromosomal engineering of mouse zygotes
Satoru Iwata, Miki Nagahara, Risako Ido, Takashi Iwamoto
This paper demonstrates that disrupting Recql5 in mice enables the generation of complex chromosomal rearrangements using CRISPR/Cas9, creating a model for studying chromoanasynthesis.
Genetics · Apr 5, 2024Peer-reviewedGenomics