SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain is Subject to Negative Selection with Predicted Positive Selection Mutations
You Li, Ye Wang, Yaping Qiu, Zhen Hui Gong, Lei Deng, Min Pan, Huiping Yang, Jianan Xu, Yang Li, Jin Li
The paper predicts hot spot residues in the SARS-CoV-2 spike protein's receptor-binding domain and identifies mutations that may enhance or reduce viral transmission.
bioRxiv · May 4, 2020 · PreprintBioinformatics