Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma
Philip Burnham, Min Seong Kim, Sean Agbor-Enoh, Helen Luikart, Hannah A Valantine, Kiran K Khush, Iwijn De Vlaminck
This study uses single-stranded DNA library preparation to analyze cfDNA in lung transplant patients, revealing increased mitochondrial and microbial cfDNA and donor-specific mitochondrial cfDNA fragments.
bioRxiv · Dec 30, 2015Genomics