In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1
Armi M Chaudhari, Minal Chaudhari, Sapna Mahera, Zuber Saiyed, Neelam Mustakali Nathani, Shantanu P. Shukla, Dhaval Patel, Chirag Patel, Madhvi N. Joshi, Chaitanya G. Joshi
The paper analyzes the C241T variant of SARS-CoV-2's 5' UTR, showing reduced interaction with host factors MADP1 and hnRNP-1, leading to lower transcription efficiency and potentially lower disease severity.
Informatics in Medicine Unlocked · Jan 1, 2021Peer-reviewedBioinformatics