Author

Shantanu P. Shukla

Northwestern UniversityORCID 0000-0002-5473-0207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alfonso MondragóniD· 1 shared Armi M ChaudhariiD· 1 shared Chaitanya G. JoshiiD· 1 shared Chirag PateliD· 1 shared Dhaval PateliD· 1 shared Dominika BorekiD· 1 shared G. MinasoviD· 1 shared K.J.F. SatchelliD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Alfonso MondragónORCID

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2 papers

Recent·Most cited

Molecular BiologyProtein SciencePeer-reviewedMay 5, 2026

Analysis of the heterogenous structural states of the hexameric ATPase PilU of the Type IV pili from Vibrio cholerae

Yirui Guo, Shantanu P. Shukla, G. Minasov…·K.J.F. Satchell

The paper determines six structural states of PilU, a retraction ATPase, revealing its homohexameric assembly and conformational flexibility, which may explain its weak ATPase activity and dependence on PilT.

1 citation

experimental assay

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BioinformaticsInformatics in Medicine UnlockedPeer-reviewedJan 1, 2021

In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1

Armi M Chaudhari, Minal Chaudhari, Sapna Mahera…·Chaitanya G. Joshi

The paper analyzes the C241T variant of SARS-CoV-2's 5' UTR, showing reduced interaction with host factors MADP1 and hnRNP-1, leading to lower transcription efficiency and potentially lower disease severity.

27 citations

viruswhole-genome sequencing

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